|Order number||Description||Quantity||Delivery time||CE|
|TB T3102||TriniLIA Auto Dimer||kit||15-20 days||x|
TriniLIA Auto Dimer
TriniLIA Auto Dimer is an immunoturbidimetric assay used for the quantitative determination of the fibrin degradation products that contain D-Dimer in human plasma on automated instruments.
D-Dimer containing moieties are formed by plasmin degradation of factor XIIIa cross-linked fibrin. Elevated levels of D-Dimer are found in clinical conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE) and disseminated intravascular coagulation (DIC). Laboratory measurements of fibrin degradation products, including D-Dimer, have significance in the initial assessment of these conditions.
TriniLIA Auto Dimer is a turbidimetric assay that utilizes antibody coated latex particles. In the presence of D-Dimer, the particles aggregate and turbidity increases. The increase in scattered light is proportional to the amount of D-Dimer in the sample. The latex particles are coated with a monoclonal antibody that reacts with fibrin D-Dimer or fragment D of fibrin. The antibody has no cross reactivity with fibrinogen. This allows for the determination of D-Dimer in human plasma.